Arguably the most famous museum in the Keys, the Ernest Hemingway Home and Museum offers an intimate look into the life of one of America’s greatest writers. Nestled in the heart of Old Town Key West, this Spanish Colonial-style mansion was Hemingway’s residence in the 1930s. Visitors can explore the rooms where Hemingway wrote many of his famous works, see his personal artifacts, and meet the descendants of his six-toed cats. The lush gardens surrounding the house add to the tranquil ambiance of this literary landmark.

The Custom House, a grand red-brick building, is a historic landmark in Key West that now houses the Key West Museum of Art & History. The museum’s exhibits chronicle the island’s history, from its maritime heritage to its role in the Cuban missile crisis. The museum also features works by local artists and rotating art exhibitions, making it a cultural hub in the heart of Key West.

The Mel Fisher Maritime Museum is dedicated to the life and discoveries of treasure hunter Mel Fisher. The museum showcases artifacts from the Spanish galleons Nuestra Señora de Atocha and Santa Margarita, which sank off the Florida Keys in the 17th century. Visitors can marvel at the recovered treasures, including gold and silver coins, emeralds, and ancient navigational instruments, while learning about the exciting history of maritime exploration and treasure hunting.

Located in Islamorada, the History of Diving Museum offers a fascinating look into the evolution of underwater exploration. The museum’s extensive collection includes antique diving helmets, underwater cameras, and early scuba gear. Interactive exhibits and educational programs provide insight into the technological advancements and daring adventures that have shaped the history of diving.

The Keys History & Discovery Center in Islamorada provides a comprehensive overview of the Florida Keys’ rich history. Exhibits cover everything from the indigenous peoples who first inhabited the islands to the construction of the Overseas Railroad and the impact of hurricanes. The center also features rotating exhibitions and a theater that shows documentaries about the region’s history and natural environment.

Crane Point Museum and Nature Center in Marathon is an oasis of natural beauty and history. The museum offers exhibits on the native flora and fauna of the Keys, as well as the cultural history of the region’s early inhabitants. The surrounding nature trails lead visitors through lush hammocks, past the historic Adderley House, and to the Marathon Wild Bird Center, where injured birds are rehabilitated.

The Fort East Martello Museum, housed in a Civil War-era fort, showcases the eclectic history of Key West. The museum’s exhibits include everything from relics of the island’s military past to local folk art. One of the museum’s most famous residents is Robert the Doll, a supposedly haunted doll that has become a local legend.

Pigeon Key, a tiny island beneath the Old Seven Mile Bridge, is a historic site that played a crucial role in the construction of the Overseas Railroad. The Pigeon Key Foundation and Marine Science Center offers guided tours that delve into the island’s history and its importance to the Keys. The center also provides marine science education programs and snorkeling opportunities in the surrounding waters.

Located 70 miles west of Key West, Dry Tortugas National Park is home to the historic Fort Jefferson, one of the largest brick masonry structures in the Americas. Accessible only by boat or seaplane, the park offers a unique blend of history and natural beauty. Visitors can tour the fort, which was used as a military prison during the Civil War, and explore the pristine coral reefs and abundant marine life that surround the island. The visitor center at the fort provides exhibits on the history and ecology of the Dry Tortugas.